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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1897 1
1911 1
1919 2
1946 1
1947 2
1948 5
1949 1
1950 3
1951 2
1952 1
1953 2
1954 4
1955 5
1956 2
1957 3
1958 1
1959 3
1960 1
1961 5
1962 3
1963 1
1964 6
1965 1
1967 5
1968 5
1969 2
1970 2
1971 1
1972 4
1973 7
1974 3
1975 19
1976 17
1977 11
1978 11
1979 24
1980 15
1981 19
1982 26
1983 28
1984 38
1985 41
1986 53
1987 48
1988 38
1989 49
1990 47
1991 51
1992 42
1993 52
1994 54
1995 75
1996 78
1997 94
1998 111
1999 117
2000 126
2001 152
2002 116
2003 157
2004 170
2005 174
2006 259
2007 219
2008 281
2009 289
2010 337
2011 358
2012 415
2013 425
2014 474
2015 492
2016 523
2017 526
2018 544
2019 556
2020 569
2021 639
2022 549
2023 524
2024 202

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8,962 results

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Page 1
Cardiogenic control of affective behavioural state.
Hsueh B, Chen R, Jo Y, Tang D, Raffiee M, Kim YS, Inoue M, Randles S, Ramakrishnan C, Patel S, Kim DK, Liu TX, Kim SH, Tan L, Mortazavi L, Cordero A, Shi J, Zhao M, Ho TT, Crow A, Yoo AW, Raja C, Evans K, Bernstein D, Zeineh M, Goubran M, Deisseroth K. Hsueh B, et al. Nature. 2023 Mar;615(7951):292-299. doi: 10.1038/s41586-023-05748-8. Epub 2023 Mar 1. Nature. 2023. PMID: 36859543 Free PMC article.
To identify potential mechanisms, we used whole-brain activity screening and electrophysiology to find brain regions that were activated by imposed cardiac rhythms. We identified the posterior insular cortex as a potential mediator of bottom-up cardiac interoceptive …
To identify potential mechanisms, we used whole-brain activity screening and electrophysiology to find brain regions that were activated by …
Insular cortex neurons encode and retrieve specific immune responses.
Koren T, Yifa R, Amer M, Krot M, Boshnak N, Ben-Shaanan TL, Azulay-Debby H, Zalayat I, Avishai E, Hajjo H, Schiller M, Haykin H, Korin B, Farfara D, Hakim F, Kobiler O, Rosenblum K, Rolls A. Koren T, et al. Cell. 2021 Nov 24;184(24):5902-5915.e17. doi: 10.1016/j.cell.2021.10.013. Epub 2021 Nov 8. Cell. 2021. PMID: 34752731 Free article.
Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and how the brain represents the state of the immune system remains unclear. Here, we show that the brain's insular cortex (InsCtx) stores immune-related information. Using activ …
Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and how the brain represents the state of the immune …
The insular cortex.
Gogolla N. Gogolla N. Curr Biol. 2017 Jun 19;27(12):R580-R586. doi: 10.1016/j.cub.2017.05.010. Curr Biol. 2017. PMID: 28633023 Free article.
Whether you see the person you are in love with, try to listen to your own heartbeat, suffer from a headache, or crave for a chocolate cookie, one part of your brain is sure to increase its activity strongly: the insular cortex. The insular cortex, or …
Whether you see the person you are in love with, try to listen to your own heartbeat, suffer from a headache, or crave for a chocolate cooki …
Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain.
Zhang MM, Geng AQ, Chen K, Wang J, Wang P, Qiu XT, Gu JX, Fan HW, Zhu DY, Yang SM, Chen QY, Zhou ZX, Fan BY, Bai Y, Xing KK, Feng JM, Wang JD, Chen Y, Lu YC, Liang Y, Cao P, Kaang BK, Zhuo M, Li YQ, Chen T. Zhang MM, et al. Neuron. 2022 Jun 15;110(12):1993-2008.e6. doi: 10.1016/j.neuron.2022.03.030. Epub 2022 Apr 19. Neuron. 2022. PMID: 35443154 Free article.
Here, we establish a long-term observational pain model in mice and find that glutamatergic projection from the insular cortex (IC) to the basolateral amygdala (BLA) is critical for the formation of observational pain. ...
Here, we establish a long-term observational pain model in mice and find that glutamatergic projection from the insular cortex
Seizure semiology, localization, and the 2017 ILAE seizure classification.
Turek G, Skjei K. Turek G, et al. Epilepsy Behav. 2022 Jan;126:108455. doi: 10.1016/j.yebeh.2021.108455. Epub 2021 Dec 8. Epilepsy Behav. 2022. PMID: 34894624 Review.
The increasing use of invasive monitoring, and specifically the use of depth electrodes and stereo-electroencephalography, has advanced our understanding of the characteristics of seizures arising from ictal foci deep to the scalp, including the cingulate, insula and operculum
The increasing use of invasive monitoring, and specifically the use of depth electrodes and stereo-electroencephalography, has advanced our …
A genetically defined insula-brainstem circuit selectively controls motivational vigor.
Deng H, Xiao X, Yang T, Ritola K, Hantman A, Li Y, Huang ZJ, Li B. Deng H, et al. Cell. 2021 Dec 22;184(26):6344-6360.e18. doi: 10.1016/j.cell.2021.11.019. Epub 2021 Dec 9. Cell. 2021. PMID: 34890577 Free PMC article.
The anterior insular cortex (aIC) plays a critical role in cognitive and motivational control of behavior, but the underlying neural mechanism remains elusive. ...
The anterior insular cortex (aIC) plays a critical role in cognitive and motivational control of behavior, but the underlying …
Fear balance is maintained by bodily feedback to the insular cortex in mice.
Klein AS, Dolensek N, Weiand C, Gogolla N. Klein AS, et al. Science. 2021 Nov 19;374(6570):1010-1015. doi: 10.1126/science.abj8817. Epub 2021 Nov 18. Science. 2021. PMID: 34793231
Whereas insular cortex responsiveness to fear-evoking cues increased with their certainty to predict harm, this activity was attenuated through negative bodily feedback that arose from heart rate decelerations during freezing. Perturbation of body-brain communicatio …
Whereas insular cortex responsiveness to fear-evoking cues increased with their certainty to predict harm, this activity was a …
Immunoception: the insular cortex perspective.
Rolls A. Rolls A. Cell Mol Immunol. 2023 Nov;20(11):1270-1276. doi: 10.1038/s41423-023-01051-8. Epub 2023 Jun 29. Cell Mol Immunol. 2023. PMID: 37386172 Free PMC article. Review.
This review will discuss our current understanding of immunoception and immunengrams, focusing on their manifestation in a specific brain region, the insular cortex (IC)....
This review will discuss our current understanding of immunoception and immunengrams, focusing on their manifestation in a specific brain re …
The Role of the Insular Cortex in Pain.
Labrakakis C. Labrakakis C. Int J Mol Sci. 2023 Mar 17;24(6):5736. doi: 10.3390/ijms24065736. Int J Mol Sci. 2023. PMID: 36982807 Free PMC article. Review.
These plastic changes are then responsible for aberrant pain perception and comorbidities. The insular cortex is consistently found activated in pain studies of normal and chronic pain patients. ...Recent progress on the role of the insula in pain from preclinical e …
These plastic changes are then responsible for aberrant pain perception and comorbidities. The insular cortex is consistently …
Linking emotional valence and anxiety in a mouse insula-amygdala circuit.
Nicolas C, Ju A, Wu Y, Eldirdiri H, Delcasso S, Couderc Y, Fornari C, Mitra A, Supiot L, Vérité A, Masson M, Rodriguez-Rozada S, Jacky D, Wiegert JS, Beyeler A. Nicolas C, et al. Nat Commun. 2023 Aug 21;14(1):5073. doi: 10.1038/s41467-023-40517-1. Nat Commun. 2023. PMID: 37604802 Free PMC article.
Responses of the insular cortex (IC) and amygdala to stimuli of positive and negative valence are altered in patients with anxiety disorders. ...
Responses of the insular cortex (IC) and amygdala to stimuli of positive and negative valence are altered in patients with anx …
8,962 results